Use of the Dermatology Life Quality Index work/study domain to estimate overall work productivity loss among patients with psoriasis: an analysis based on real-world data

Psoriasis is a chronic autoimmune disease that is associated with substantial economic burden related to work productivity loss (WPL). WPL is commonly measured using the Work Productivity and Activity Impairment (WPAI) questionnaire. However, WPAI does not measure outcomes among unemployed patients, and may therefore underestimate the burden of psoriasis. This study evaluated the relationship between the Dermatology Life Quality Index (DLQI) questionnaire work/study domain and WPL using the WPAI, as DLQI assesses the impact of psoriasis on the ability to work/study regardless of employment status, but does not estimate WPL. Data were drawn from the Adelphi Psoriasis Disease Specific Programme survey. A positive linear relationship was observed between DLQI work/study scores and WPAI results, showing that higher DLQI scores were associated with greater percent WPL. These findings suggest that the DLQI work/study domain can be used to estimate overall WPL among patients with psoriasis, including those who cannot work because of their disease.